It's why I will reinforce my thoughts in having MJ be a Chani for the sake of SM4. Make her someone in the background, someone who is observant of who Spider-Man is in how he operates; but use it as something that can be built upon for later on.As for Zendaya, my only reservation with bringing her "MJ" back is that I don't want to see Peter's sacrifice of that relationship at the end of NO WAY HOME suddenly undone. I think you risk basically ruining that movie's ending if you take that back. Under no circumstances would I want to see the character regain her memories of her prior relationship with Peter. Now, you could do a story where she builds a new relationship with Peter, but his decision to leave her alone at the end of NO WAY HOME also makes me hesitant. It's tricky to thread all those needles, which is why I'd favor leaving her character out of the next movie (perhaps to be revisited in 5). Let Peter spend a movie away from her and grow with some new supporting characters.
It's honestly why I am fully down for Sable here. I think she'd actually serve as a good "Counter-balance" to show a harsher side to those Parker/Spider-Man meets on the women side. Similar to Felicia; if they use the Symbiote Suit to show Peter going into darker roads that invites the likes of Black Cat.