Three ways a comedy club can go--all problematic:
1) Stand-up, like Improv or Bonkers. Limited capacity. If you make the guys repeat their sets, still lucky to get two 90-minute shows a night. And, having seen a few touring comedians lately, I don't know a one who doesn't touch on subjects that Comcast would want to avoid in its branded venues. CityWalk more adult than WDW but I'm sure there are still limits.
2) An improv troupe, like Comedy Warehouse. Hard to make shows long enough to make money--CW was the worst performing bar in PI for this reason. Also, it you have multiple shows, need plenty of guests wandering around--can't rely on being a destination. Not sure modern CityWalk has that.
3) A de facto "Best of SNL" show. Without the original actors, would be cringe.
I'm with Joe, don't see this working. Can't imagine an escape room would have the capacity to be worth it, either.