See--I think so long as Ryan can convince Hugh in it being a fun time that allows him to shoot the breeze (and to have a good payday); it won't be as much of an issue.
Secret Wars, more than probably; but I'd argue they could pull off another go with the two of them together depending on how they execute the plot. Plus as
@Nick says; this film is a overnight success with how much financial benefitting is coming immediately with the film already earning over 200 million dollars.
Depending on circumstances, I genuinely wonder if a GOTG2 like turnaround could be viable where it gets fastened to a Summer/Fall 2027 window.