I gotta agree that an indoor, Kilimanjaro Safari-style attraction with some interactive/shoot 'em up dark ride elements and lavish sets/AAs would be the best way to build a Pokemon E-ticket.
The question is whether Pokemon would go into the MIB/Springfield plot, serve as a Toon Lagoon replacement or be incorporated into the 3rd gate. There's no real concrete option, but the success of Pokemon Go has to have Comcast execs contemplating where Pokemon could fit into Universal Orlando